Announcing the 2022 Amanda Proudfoot Tribute Award Winner for Advances in Chemokine Biology by a Trainee
Mélanie Bruchard, PhD
INSERM U1231, Dijon, France
Dr. Mélanie Bruchard obtained her Ph.D. in immuno-oncology in France in 2013 from the University of Burgundy. Mélanie then joined the laboratory of Prof. Hergen Spits for her post-doctoral training at the Academic medical center (AMC) in Amsterdam, Netherlands, where she worked on studying how innate lymphoid cells (ILC) can act as antigen-presenting cells. In 2016, Mélanie returned to France to study the importance of type 3 ILC in the response to chemotherapy. She demonstrated that ILC3s are a crucial component of the immune response triggered by Cisplatin, a commonly used chemotherapy.
Melanie is now focusing on deciphering the cellular and molecular events leading to the spatial organization of the immune infiltrate induced by ILC3.
Oral Presentation at Cytokines 2022: RECRUITMENT AND ACTIVATION OF TYPE 3 INNATE LYMPHOID CELLS PROMOTES ANTI-TUMOR IMMUNE RESPONSES AFTER A CISPLATIN TREATMENT
Amanda Proudfoot is internationally recognized for her important contributions to the field of chemokine biology. Her research focused on the development of anti-inflammatory and anti-infective therapeutic agents and many of the advances in chemokine biology trace back to seminal discoveries made by her. Her group identified and characterized novel chemokines, including CXCL4 and CXCL8, and cloned the chemokine receptors CCR1, CCR2 and CCR4. She provided the first evidence that inhibition of HIV infection of primary macrophages could be achieved through inhibition of CCR5, leading to a new paradigm in the search for HIV inhibitors. Amanda’s research led to the elucidation of several important aspects of the immune system.
Description/Criteria: This ICIS trainee award is dedicated to the memory of Amanda Proudfoot (1949-2019), who is internationally recognized for her important contributions to the field of chemokine biology. This award will be bestowed on an ICIS Student/Postdoc member whose research on chemokine biology has had an impact on the field early in his/her career. Graduate students and postdoctoral fellows are eligible for this Award. This annual award is presented at the annual ICIS Meeting. Funding for this award is provided by friends and colleagues of the late Amanda Proudfoot. READ MORE
Award: $1,500 and a plaque made possible through the generosity of the friends and colleagues of the late Amanda Proudfoot. The Awardee will be invited for an Oral presentation during the Meeting.
