Co-chairs: Mark Kaplan, PhD, Professor and Chair, Department of Microbiology and Immunology, Indiana University, USA & Daniella Schwartz, MD, Assistant Professor, Division of Rheumatology and Clinical Immunology, Departments of Medicine and Immunology, University of Pittsburgh, USA

Mark Kaplan, PhD, Professor and Chair, Department of Microbiology and Immunology, Indiana University, USA
Mark Kaplan, PhD, Professor and Chair, Department of Microbiology and Immunology, Indiana University, USA (Co-Chair)
Daniella Schwartz, MD, Assistant Professor, Division of Rheumatology and Clinical Immunology, Departments of Medicine and Immunology, University of Pittsburgh, USA
Daniella Schwartz, MD, Assistant Professor, Division of Rheumatology and Clinical Immunology, Departments of Medicine and Immunology, University of Pittsburgh, USA, (Co-Chair)

Tuesday, June 18th 3:30 pm to 5:00 pm at the San Francisco Marriott Marquis, San Francisco, USA

International Cytokine & Interferon Society (ICIS) Symposium at FOCIS 2024

“IL-9: From Birth to Breath”

Symposium Description:

Although IL-9 was first described in the late 1980s, its regulation and functions are still not well defined. Initially thought to be a mast cell and T cell growth factor, IL-9 was subsequently reclassified as a type 2 cytokine after extensive data implicated it in atopic dermatitis, food allergy, and allergic asthma. More recently, work has implicated IL-9 as a major player in autoimmunity and antitumor immunity. New endotype-based classification systems have led many leaders in the field to speculate that “IL-9-high” endotypes have clinically relevant translational applications to precision medicine treatments of allergic, autoimmune, and malignant conditions. This has led to a renaissance of papers defining beneficial and pathogenic functions of IL-9 in disease. This symposium will focus on recent developments in IL-9 biology including a role for IL-9 in pregnancy and the function of IL-9 in allergic disease.

Co-chairs:

Mark Kaplan, PhD, Professor and Chair, Department of Microbiology and Immunology, Indiana University, USA

Daniella Schwartz, MD, Assistant Professor, Division of Rheumatology and Clinical Immunology, Departments of Medicine and Immunology, University of Pittsburgh, USA

Speakers

  • 3:30 pm Nardhy Gomez-Lopez, PhD, Professor, Department of Obstetrics and Gynecology, Washington University at St. Louis, USA
    A Novel Mechanism for Preterm Labor and Birth Driven by IL-9 at the Maternal-Fetal Interface
  • 3:45 pm Lionel Apetoh, PhD, Professor, Department of Microbiology and Immunology, Indiana University, USA
    IL-9-producing CD4 T cells in cancer immunotherapy
  • 4:00 pm Daniella Schwartz, MD, Assistant Professor, Division of Rheumatology and Clinical Immunology, Departments of Medicine and Immunology, University of Pittsburgh, USA
    Epigenetic control of IL-9 in health and disease
  • 4:15 pm Matthew Olson, PhD, Assistant Professor, Department of Biology, Purdue University, USA
    Cooperative roles of IL-1 and IL-2 in the differentiation and function of IL-9-secreting CD4 T cells
  • 4:30 pm  Paula Licona Limon, PhD, Associate Professor, Instituto de Fisiologia Celular, Universidad Nacional Autónoma de México (UNAM), MEXICO
    Lineage markers for Th9 cells: the PKA/PKIB pathway
  • 4:45 pm Josalyn Cho, MD, Associate Professor, Department of Internal Medicine-Pulmonary, Critical Care and Occupational Medicine, University of Iowa, USA
    Allergen induces IL9 expression in pathogenic airway Th2 cells in asthma