Ryan G. Gaudet, Ph.D.
Yale University Systems Biology Institute
West Haven, USA
Dr. Ryan Gaudet is a Howard Hughes Medical Institute Fellow of The Helen Hay
Whitney Foundation in Dr. John MacMicking’s lab in the Departments of
Immunobiology and Microbial Pathogenesis at Yale University. His postdoctoral
research investigated interferon-induced cell-autonomous defense pathways that
protect human tissue cells from bacterial pathogens.
Ryan received his Ph.D. from the University of Toronto under the supervision of Scott
Gray-Owen, Ph.D., where he was a CIHR Banting and Best Graduate Fellow. During
his graduate studies, Ryan discovered that bacterial heptose metabolites are a
novel class of pathogen-associated molecular patterns that activate innate
immunity. Moreover, he delineated the host signaling cascade, anchored by the
adaptor protein TIFA, that detects these metabolites upon their contamination of
the host cytosol. Ryan completed his Master’s degree with Dr. Jody Berry at the
University of Manitoba in the Department of Medical Microbiology, and his
undergraduate studies with Dr. Frederick Markham at the University of Prince
Edward Island in the Department of Biology.