Understanding and Modulating Cytokine Activity through Structural Knowledge – ICIS Guest Symposium at AAI 2023
Saturday, May 13; 10:15 AM – 12:15 PM Eastern Time; Room 102AB
Chairs:
- Juan L. Mendoza, University of Chicago, USA
- Ignacio Moraga, University of Dundee, United Kingdom
Speakers:
- Matthew C. Franklin, Regeneron, Structural insights into the assembly of gp130 family cytokine signaling complexes
- Juan L. Mendoza, University of Chicago, The native JAK-JAK geometry in the type III IFN signaling complex limits the functional potency
- Dylan Daniel, CytomX Therapeutics, Designing conditionally activated probody cytokines to localize antitumor activity to cancers
- Ignacio Moraga, University of Dundee, United Kingdom, Manipulating cytokine activities in different extracellular microenvironments
- Jamie B. Spangler, Johns Hopkins University, Dissecting immune biology using de novo engineered cytokines