Please join us on December 10 for this virtual meeting
Viewing at: https://nci.rev.vbrick.com/#/webcasts/mousemodelsoflupus
Mouse models of lupus 10 years later: key advances in understanding pathogenesis & remaining uncertainties in translation
In 2010, a meeting was held at the National Library of Medicine focused on mouse models of lupus and their relevance to human disease. At that time, the overall consensus was that mouse models are indeed useful for the investigation of SLE and would lead to a better understanding of disease pathophysiology and more effective treatment options. However, progress continues to be slow, and while several promising therapeutic approaches were effective in murine disease, they continue to disappoint in the human trials. Moreover, treatment today for several key disease manifestations (e.g. brain, kidney) is still based on non-specific immunosuppressive modalities. It is the purpose of this meeting to revisit murine models of lupus and open the dialogue as to their real value in understanding and treating human disease.
Schedule: 8:30-5 EST
8:30-9 pm Opening Address: Hans Anders
9-10:20 Session I Characterizing Immune Aberrations in Both Mice and Humans
Speakers: Mark Shlomchik, Jason Weinstein, Laurence Morel, Michelle
Kahlenberg
10:20-10:40 Session I Discussion
10:40-10:50 Break I
10:50-12:10 Session II SLE and Infections
Speakers: Stefania Gallucci, Gregg Silverman, Martin Kriegel, Xin Luo
12:10-12:30 Session II Discussion
12:30-1 Lunch Break
1-2:20 Session III Evaluation of Novel Drug Targets from Mice to Human
Speakers: Chaim Putterman, Mariana Kaplan, Anne Davidson, Paul Hoover
2:20-2:40 Session III Discussion
2:40-2:50 Break II
2:50-4:10 Session IV Leveraging SLE Patients and Mouse Models Together
Speakers: Deepak Rao, Betty Diamond, Eric Meffre, Jeremy Duffield
4:10-4:30 Session IV Discussion
4:30-5 Keynote Address: Eric Moran
