Website University of Alabama at Birmingham
My laboratory is seeking a self-starting, highly motivated and technically proficient PhD level immunologist to study the role of type I interferons and Trem1 in modulation of cancer/infection/autoimmune disease. The candidate will apply variety of tools including molecular, cellular and biochemical techniques alongside immunofluorescence imaging, flow cytometry and bioinformatics in preclinical in vivo models to address these key questions. (S)he will work in a fast-paced and highly collaborative research environment and will be expected to present their findings in high-impact journals and at both internal and external scientific conferences.
· PhD in immunology or related field
· A high-level understanding of key concepts in immunology.
· Competent animal handling skills including intraperitoneal, sub cutaneous and tail vein injection.
· Experience in ex vivo processing of tumor and lymphoid tissues
· Expertise with primary cell isolation and culture assays, including co-culture and transwell assays.
· A strong desire to learn, it is not expected that the successful candidate will have experience with all of the required techniques however they must be willing to expand their technical and scientific capabilities
· Working knowledge of common murine transgenic and floxed mouse models.
· Expertise with analysis of high dimensional datasets including single cell RNA-seq and multi-parameter flow cytometry.
· Experience performing high resolution immunofluorescence microscopy and data analysis
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