To deliver on the promise of mRNA science
Moderna is seeking applicants for Senior Research Associate for position based at its Cambridge, MA site. The individual in this role will support platform, discovery programs through the development and execution of bioanalytical assays and interface with internal as well as external stakeholders (partners, CROs). This position will contribute to the nonclinical team through the performance and development of nucleic acid-based assay development. The individual will work with scientists within the discovery Bioanalytics team and broader nonclinical group as well as other functional groups to ensure the highest level of quality of these assays. The successful candidate must have experience in assay development specifically hands on experiences in performing nucleic acid and protein isolation from in-vivo samples for RT-qPCR and ELISA.
The candidate must thrive in a fast pace environment with high expectations. Integrity, ability to share experimental issues and troubleshoot, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values to thrive in our Team.
Here’s What You Will Do:
Design, execute and analyze PCR based experiments to quantitate mRNA in biological samples.
Routinely perform DNA/RNA extraction from tissue or plasma or other biologically relevant matrices and lead PCR based method development
Work with other colleagues in ligand binding assay team and provide support as needed.
Lead bioanalytical testing using established methods or help design new methods as needed to generate high quality data to support internal studies.
Work closely with more senior colleagues and lead method development and troubleshooting for discovery programs.
Assist in method qualification as needed.
Provide summary presentations and detailed reports to internal and external stake holders.
Participate in the drug development project management nonclinical activities.
Establish quantitative methods to detect biologically relevant molecules.
Generate, analyze, interpret, and present high quality, timely experimental data to multidisciplinary teams. Ensure that data generated internally and externally are scientifically rigorous, in line with study design, regulatory expectations and follows industry’s best practice.
Responsible for multiple assay-related aspects for platform and development programs
Be accountable for all experimental and project related needs assigned
Maintain accurate documentation of experiments in electronic lab notebook (ELN)
Here’s What You’ll Bring to the Table:
BS/MS degree in biology, immunology, biochemistry, pharmacology, or a related field.
BS with 2-5 years of experience or MS with 1-3 years hands on experience in assay development
Hands on experiences in bioassay development and knowledge of assay qualification/validation aspects
Hands on experiences with PCR (qPCR/ddPCR) based assay development, DNA/RNA extraction/handling, cell culture techniques, western blotting, immunoassays such as ELISA and other analytical techniques
Ability to develop methods, write concise research protocols and synthesize data in accordance with good laboratory practice.
Familiar with assay development, qualification and validation guidelines from regulatory agencies and statistical analysis
Knowledge of biochemistry, drug development, pharmacology and regulatory (a plus)
Ability and desire to troubleshoot assays
Experience with interfacing with CROs is a plus
Strong ability to analyze and communicate complex results through written and oral communication
Proven ability to develop and work independently and to collaborate cross-functionally to accomplish goals in a timely manner
Proficient in standard Microsoft Office tools: Word, Excel, PowerPoint, PRISM, and SoftMax.
Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:
Highly competitive and inclusive medical, dental and vision coverage options
Flexible Spending Accounts for medical expenses and dependent care expenses
Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
Family care benefits, including subsidized back-up care options and on-demand tutoring
Free premium access to fitness, nutrition, and mindfulness classes
Exclusive preferred pricing on Peloton fitness equipment
Adoption and family-planning benefits
Dedicated care coordination support for our LGBTQ+ community
Generous paid time off, including:
• Vacation, sick time and holidays
• Volunteer time to participate within your community
• Discretionary winter shut down
• Paid sabbatical after 5 years; every 3 years thereafter
Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
401k match and Financial Planning tools
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Complimentary concierge service including home services research, travel booking, and entertainment requests
Free parking or subsidized commuter passes
Location-specific perks and extras!
Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.
In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna’s capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.
Moderna’s mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
To apply for this job please visit modernatx.wd1.myworkdayjobs.com.