Website TWINCORE, Centre for Experimental and Clinical Infection Research GmbH; a joint venture between the Helmholtz Centre for Infection Research (HZI), Braunschweig, and the Hannover Medical School (MHH)

TWINCORE, Centre for Experimental and Clinical Infection Research GmbH (TWINCORE) is a joint venture between the Helmholtz Centre for Infection Research (HZI), Braunschweig, and the Hannover Medical School (MHH). The mission of this centre is to enhance the cooperation between both founding institutions and to perform translational infection research aiming at the improvement of prevention, diagnostics and therapy of human infectious diseases. The aim is to develop innovative molecular diagnostics, novel vaccination strategies and new treatment options. Visit our website for further information:

A position is to be filled in the “Institute for Experimental Infection Research” headed by Prof. Dr. Ulrich Kalinke, as soon as possible. The job details are as follows:

Postdoc Position

The position is open within a project which addresses the interaction of innate and adaptive immune mechanisms with the pathogenesis of CNS disorders in a cross-center approach. The project is entitled “Immunity, Infection and Inflammation in CNS Disorders”.

It is funded by the Helmholtz Association and will be performed in close cooperation with different Helmholtz Centers (e.g. DZNE and HZI).

Background of the Project

The recent discovery that innate and adaptive immunity play key roles in the pathogenesis of neurodegenerative and psychiatric diseases opened a new avenue for research and development of diagnostic and therapeutic interventions. There are now indications that innate immune signals and infection-related inflammatory processes inside and perhaps outside of the brain contribute to neurodegenerative and psychiatric diseases. In particular microglial cells, but also astrocytes represent the interface between the nervous and the immune system.

The objective of the project is to mechanistically explore the complex and fascinating ways by which neurodegenerative and inflammatory processes are mutually interconnected through the interaction of immune, stromal and parenchymal cells in the CNS, and how they are influenced by immune reactions outside the CNS.

Essential criteria for applying:

– PhD in immunology, biochemistry or neuroscience, or a MD

– Experiences in working with: S2 pathogens, S2 laboratories, histology and flow cytometry, behavioral studies with animals, RNA sequencing and mice are preferable

– social competence and excellent team skills

– Motivation and flexibility, a high degree of dedication and productivity

– Excellent communication skills in English

– Readiness to work and communicate in an collaborative, interdisciplinary, dynamic and international environment.

Disabled persons shall be given preference if their skills and qualifications are equivalent to those of non-disabled candidates. TWINCORE is an equal opportunity employer. Part-time employment is possible upon request.


Starting date: as soon as possible

The contract will be for 2 years.

Salary: E13 TVöD / Bund

Workplace: Hannover

Probation period: 6 months

Closing date: 24.11.2018

Further information will be provided by Prof. Dr. Ulrich Kalinke ([email protected]).

Please address you application referring to code 70/2018 to Helmholtz-Zentrum für Infektionsforschung GmbH, Personalabteilung, Inhoffenstraße 7, 38124 Braunschweig or in one (1) pdf document via eMail to: [email protected].

To apply for this job email your details to