Website East Carolina University
We are currently seeking a highly motivated post-doctoral fellow to investigate pathways by which environmental carbon nanoparticles induce pulmonary disease and alter innate immune responses of alveolar macrophages. These studies have recently been funded by a multi-year NIH grant and will involve various strains of macrophage-specific knock-out mice in a pre-clinical lung disease model plus studies of human alveolar macrophages from healthy controls and selected clinical patients. Laboratory methodology includes standard molecular and biochemical techniques including use of miRNA and lenti-viral manipulations in vitro and in vivo, confocal imaging, flow cytometry, ELISAs, PCR, automated protein determination (WES), immunostaining, and laser capture microdissection.
The applicant should preferably have a background in molecular biology, experience with mouse models, and a strong track record of publications. A highly competitive salary and benefits will be offered based on the NIH postdoctoral pay scale http://grnts.nih.gov/grants/guide/notice-files/NOT-OD-15-048.html. Approximately 95% of the postdoctoral scholar’s time will be devoted to research. Approximately 5% of the postdoctoral scholar’s time will be devoted to mentoring of undergraduate and graduate research students in the laboratory.
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